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The ImmEdge?Pen, a hydrophobic barrier pen for immunohistochemistry and in situ hybridization, is designed for use with frozen or paraffin-embedded tissue sections mounted on glass slides. The ImmEdge?Pen provides a heat-stable, water-repellent barrier that keeps staining reagents localized on the tissue sections, prevents mixing of reagents when differentially staining two sections on the same slide, and allows use of less reagents per section.
The lightly colored barrier is insoluble in alcohol and acetone, but is completely removed by all commonly used xylene and “xylene substitute” clearing agents. The ImmEdge? Pen contains no ozone-depleting solvents and is compatible with enzyme or fluorescent-based detection systems.
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ImmEdge Hydrophobic Barrier Pen H-4000 2 pen set
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