產(chǎn)品編號:KMPH1835
產(chǎn)品名稱:Recombinant Human ACE2 Protein, His-tag
產(chǎn)品別稱:Angiotensin-converting enzyme 2, ACE2
規(guī)格:100ug,1mg
物種:Human
宿主:HEK293 Cells
序列:18-740AA
來源:A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was
expressed with a polyhistidine tag at the C-terminus.
純度:≥95% as determined by SDS-PAGE
內(nèi)毒素水平:< 1.0 EU per μg of the protein as determined by the LAL method.
緩沖體系:Lyophilized from sterile PBS, pH 7.4.
純化方式:His Tag Purification
產(chǎn)品背景:
Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell
membranesofcellslocatedinthelungs,arteries,heart,kidney,andintestines.
ACE2lowersbloodpressureby catalyzing thehydrolysisof angiotensinIIinto
angiotensin (1–7). ACE2 counters the activity of therelated
angiotensin-convertingenzyme(ACE)by reducingtheamountofangiotensin-II and
increasing Ang(1-7), making it a promising drug target for treating cardiovascular
diseases.ACE2alsoserves asthe entrypointintocellsforsome coronaviruses, including
HCoV-NL63, SARS-CoV, and SARS-CoV-2.
保存條件:Store the product under sterile conditions after opening at -20℃ to -80℃ for 12
months. Avoid repeated freeze-thaw cycles.
運輸條件:Liquid product is shipped on dry ice; Lyophilized powder is shipped on ice packs